Divalproex sodium might cause drowsiness and dizziness. Don’t consume alcohol although using this drug since it can raise your threats of slowed reflexes, poor judgment, and sleepiness.
The mechanism of this interaction just isn't effectively understood. Serum valproic acid concentrations ought to be monitored regularly following initiating carbapenem therapy. Different antibacterial or anticonvulsant therapy ought to be deemed if serum valproic acid concentrations drop drastically or seizure Management deteriorates [see Warnings and Safeguards (5.13)].
Treat the manic section of bipolar dysfunction. A manic episode is often a timeframe the place your mood is amazingly powerful. This will include an elevated or an irritated mood.
Being a standalone and adjunctive therapy to treat both equally straightforward and complex absence seizures in Grown ups and pediatric patients.
In the last decades, the drug's utilization has expert a substantial upswing, don't just like a temper stabilizer but in addition as a alternative for lithium treatment. Even so, a retrospective cohort study involving persons with bipolar disorder unveiled that Those people below lithium cure exhibited a decreased chance of suicide tries and suicide-associated deaths when compared with All those getting divalproex sodium.
8)]. The advantage of enhanced therapeutic effect with increased doses should be weighed towards the opportunity of a greater incidence of adverse reactions.
Phone your Health care supplier at once For those who have any of such signs and symptoms: significant tummy pain that You might also sense in your back
If these effects are moderate, They might go away inside a couple of days or two or three months. When they’re more severe or don’t disappear, talk with your doctor or pharmacist.
The body may perhaps approach this drug much more slowly but surely and you will have more of a sedative effect. Your health practitioner may perhaps commence you over a decreased dosage and improve it slowly to ensure too much of this drug doesn’t Construct up in Your system. Far too much with the drug in The body can result in hazardous effects.
In case you don’t take it in the least or miss doses: When you don’t consider this drug on a regular basis, you miss doses, otherwise you halt taking it out of the blue, there can be significant challenges.
Psychological retardation with significant seizure Issues—Use with caution. Might boost danger for more major side effects.
Divalproex sodium, valproate sodium, and valproic acid products and solutions are absorbed by the human body in various ways and can't be substituted for each other. If you might want to swap from a person products to a different, your physician might need to adjust your dose.
Since clients were staying titrated off An website additional antiepilepsy drug over the very first percentage of the trial, it truly is impossible, in many scenarios, to determine no matter whether the subsequent adverse reactions could be ascribed to Depakote by yourself, or The mix of valproate along with other antiepilepsy prescription drugs.
are pregnant or might turn out to be Expecting. DEPAKOTE may well damage your unborn child. See “2. Depakote may possibly damage your unborn infant” above For more info.